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GMU:Synthetic Biology/Bacteria Game (view source)
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'''Swimming''' of the cells can be described as a '''biased random walk''' in a '''spatial gradient''' of media. The microbe runs in favorable directions towards high concentrations of '''attractant''' (i. e. nutrient) and away from '''repellents''' (i. e. antibiotic). Straight '''runs''' are only interrupted by '''short tumbles''' where the cell reorients randomly for the next run. The probability for tumbling increases with higher repellent concentrations. Likewise the tumbling frequency rises during runs down attractant gradients (see figure below). As a result, the cell almost swims along curly '''trajectories'''. | '''Swimming''' of the cells can be described as a '''biased random walk''' in a '''spatial gradient''' of media. The microbe runs in favorable directions towards high concentrations of '''attractant''' (i. e. nutrient) and away from '''repellents''' (i. e. antibiotic). Straight '''runs''' are only interrupted by '''short tumbles''' where the cell reorients randomly for the next run. The probability for tumbling increases with higher repellent concentrations. Likewise the tumbling frequency rises during runs down attractant gradients (see figure below). As a result, the cell almost swims along curly '''trajectories'''. | ||
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Limitations | [[File:Figure swarm.jpg | thumb | 400px | figure: swarming bacteria (Adlung, 2010]] | ||
===Limitations=== | |||
* “culturing” / “breeding” meaning selection of best swarmers | * “culturing” / “breeding” meaning selection of best swarmers | ||
** evolutionary effect on molecular level (i. e. signal network properties) | ** evolutionary effect on molecular level (i. e. signal network properties) | ||