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Revision as of 15:44, 31 October 2017
, 31 October 2017→Eduardo Kac, GFP Bunny
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===Eduardo Kac, GFP Bunny=== | ===Eduardo Kac, GFP Bunny=== | ||
[[File:gfp-bunny-copy-oslolux.wordpress.com-eduardo-kac.png|thumb|Fig. 4. GFP bunny. Source: http://oslolux.wordpress.com/eduardo-kac ]] | |||
The transgenic artwork "GFP Bunny" was completed in February 2000 with the birth of rabbit named "Alba" (Fig. 4.). The project is an outcome of Kac’s collaboration with zoosystemician Louis Bec and scientists Louis-Marie Houdebine and Patrick Prunet. The rabbit has an altered genomics carrying a fluorescent GFP, a same protein, which was used to modify GloFish. Genetically modified Alba is an albino rabbit with no skin pigment and pink eyes. Under the day light it would look white and under the blue light with maximum excitation of 488 nm, the rabbit would glow with a bright green light (Kac 2000). | The transgenic artwork "GFP Bunny" was completed in February 2000 with the birth of rabbit named "Alba" (Fig. 4.). The project is an outcome of Kac’s collaboration with zoosystemician Louis Bec and scientists Louis-Marie Houdebine and Patrick Prunet. The rabbit has an altered genomics carrying a fluorescent GFP, a same protein, which was used to modify GloFish. Genetically modified Alba is an albino rabbit with no skin pigment and pink eyes. Under the day light it would look white and under the blue light with maximum excitation of 488 nm, the rabbit would glow with a bright green light (Kac 2000). | ||
In the description of the project Kac writes: | In the description of the project Kac writes: | ||
"My transgenic artwork /GFP Bunny/ comprises the creation of a green fluorescent rabbit, the public dialogue generated by the project, and the social integration of the rabbit. | "My transgenic artwork /GFP Bunny/ comprises the creation of a green fluorescent rabbit, the public dialogue generated by the project, and the social integration of the rabbit."* | ||
While the project generated a huge attention in the media and was followed by a number of interpretations,3 the social integration of the rabbit has failed as it was never released from the laboratory. | While the project generated a huge attention in the media and was followed by a number of interpretations,3 the social integration of the rabbit has failed as it was never released from the laboratory.* Despite that Alba, like any other rabbit, was seeking interaction and was, for example, sitting comfortably on Kac’s hands (Kac 2000). | ||
For genetic modification of Alba, scientists integrated GFP into the genome through zygote microinjection, the method most extensively used in the production of transgenic animals including rabbits. The method suggests the in vitro fertilization which is done outside of the organism and therefore could be easily combined with the somatic cell nuclear transfer method used for cloning Dolly. | For genetic modification of Alba, scientists integrated GFP into the genome through zygote microinjection, the method most extensively used in the production of transgenic animals including rabbits. The method suggests the in vitro fertilization which is done outside of the organism and therefore could be easily combined with the somatic cell nuclear transfer method used for cloning Dolly. | ||
There is a number of controversial discussions around “GFP Bunny” project. On one hand the photo of a fluorescent rabbit is manipulated digitally. Secondly, there are different versions of how long the rabbit was alive. Finally, according to Wired magazine, it is not clear if the rabbit was genetically modified as an artistic project from the beginning on. | There is a number of controversial discussions around “GFP Bunny” project. On one hand the photo of a fluorescent rabbit is manipulated digitally. Secondly, there are different versions of how long the rabbit was alive. Finally, according to Wired magazine, it is not clear if the rabbit was genetically modified as an artistic project from the beginning on.* Nevertheless, the project gained enough attention from media to consider the project as one of the most influential in Bioart. | ||
*http://www.ekac.org/gfpbunny.html#gfpbunnyanchor | |||
*http://www.ekac.org/gfpbunny.html | |||
*https://today.duke.edu/2000/11/bunnyn03.html | |||
*https://www.wired.com/2002/08/rip-alba-the-glowing-bunny/ | |||
===Revital Cohen and Tuur Van Balen, Sterile=== | ===Revital Cohen and Tuur Van Balen, Sterile=== | ||