GMU:Synbio: Difference between revisions

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1) Well, i.e. for diagnosis of genetic diseases. Recent studies showed, that DNA sequencing from the blood of pregnant women can be used to determine whether the fetus (baby) has the predisposition for a certain genetic disease. Keep in mind, that the DNA is sort of the genetic building plan of evey cell. So you can get information about this building plan and whether it has some errors here and there. Find some information about DNA Sequencing from blood [http://www.pnas.org/content/105/42/16266.full here].

2) Sequencing not the DNA, but the RNA is also very interesting, as the amount of RNA present in a cell gives you information about the gene expression (= the genes turned on and those turned of at a certain timepoint). RNA is the molecule that is used to translate the messages coded on the DNA in a from, that the inner cell machinary can read this massage and make the proteins. Proteins are the effector molecules and can be seen as the little machines, controlling the behaviour of a cell (i.e. energy production, movement, cell division- nearly everything). Strongly simplified, one can say, that one Gene codes for a certain RNA and that RNA codes for a certain protein.

2) Sequencing not the DNA, but the RNA is also very interesting, as the amount of RNA present in a cell gives you information about the gene expression (= the genes turned on and those turned off at a certain timepoint). RNA is the molecule that is used to translate the messages coded on the DNA in a from, that the inner cell machinary can read this massage and make the proteins. Proteins are the effector molecules and can be seen as the little machines, controlling the behaviour of a cell (i.e. energy production, movement, cell division- nearly everything). Strongly simplified, one can say, that one Gene codes for a certain RNA and that RNA codes for a certain protein.

DNA --> RNA --> Protein

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 ) Well, i.e. for diagnosis of genetic diseases. Recent studies showed, that DNA sequencing from the blood of pregnant women can be used to determine whether the fetus (baby) has the predisposition for a certain genetic disease. Keep in mind, that the DNA is sort of the genetic building plan of evey cell. So you can get information about this building plan and whether it has some errors here and there. Find some information about DNA Sequencing from blood [http://www.pnas.org/content/105/42/16266.full here].
-) Sequencing not the DNA, but the RNA is also very interesting, as the amount of RNA present in a cell gives you information about the gene expression (= the genes turned on and those turned of at a certain timepoint). RNA is the molecule that is used to translate the messages coded on the DNA in a from, that the inner cell machinary can read this massage and make the proteins. Proteins are the effector molecules and can be seen as the little machines, controlling the behaviour of a cell (i.e. energy production, movement, cell division- nearly everything). Strongly simplified, one can say, that one Gene codes for a certain RNA and that RNA codes for a certain protein.
+) Sequencing not the DNA, but the RNA is also very interesting, as the amount of RNA present in a cell gives you information about the gene expression (= the genes turned on and those turned off at a certain timepoint). RNA is the molecule that is used to translate the messages coded on the DNA in a from, that the inner cell machinary can read this massage and make the proteins. Proteins are the effector molecules and can be seen as the little machines, controlling the behaviour of a cell (i.e. energy production, movement, cell division- nearly everything). Strongly simplified, one can say, that one Gene codes for a certain RNA and that RNA codes for a certain protein.
 DNA --> RNA --> Protein