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→General Information and some specific Information about future vision of Personalized Medicine
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Unnormal gene expression is a typical indicator for a disregulation in a cell and can therefor be indicator for a disease. In many diseases the gene expression (and therefor the gene regulation) is unnormal. But not only diseases lead to different gene expression: When you eat and drink, when you jump into cold water and in other situations gene expression might be altered. | Unnormal gene expression is a typical indicator for a disregulation in a cell and can therefor be indicator for a disease. In many diseases the gene expression (and therefor the gene regulation) is unnormal. But not only diseases lead to different gene expression: When you eat and drink, when you jump into cold water and in other situations gene expression might be altered. | ||
Coming back to the point: Sequencing RNA from human blood is possible since some years. In the future, as automated sequencing gets better and cheaper, that could give us the oppotunity to have a sort of online-look onto our gene expression. We would simply take blood samples and put them into a full-automatic sequencer. | Coming back to the point: Sequencing RNA from human blood is possible since some years. In the future, as automated sequencing gets better and cheaper, that could give us the oppotunity to have a sort of online-look onto our gene expression. We would simply take blood samples and put them into a full-automatic (pocket?) sequencer. | ||
Today, RNA analysis from blood samples is used i.e. for the [http://en.wikipedia.org/wiki/HIV_test HIV-diagnosis] and is also taken into account for [http://en.wikipedia.org/wiki/HIV_test cancer diagnosis]. In general, if the RNA sequencing from blood will get better and better, we will probably be able to look at our gene expression profile online! | Today, RNA analysis from blood samples is used i.e. for the [http://en.wikipedia.org/wiki/HIV_test HIV-diagnosis] and is also taken into account for [http://en.wikipedia.org/wiki/HIV_test cancer diagnosis]. In general, if the RNA sequencing from blood will get better and better, we will probably be able to look at our gene expression profile online! | ||